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SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19.
Ravichandran S, Tang J, Grubbs G, Lee Y, Pourhashemi S, Hussaini L, Lapp SA, Jerris RC, Singh V, Chahroudi A, Anderson EJ, Rostad CA, Khurana S. Ravichandran S, et al. Nat Immunol. 2021 Nov;22(11):1452-1464. doi: 10.1038/s41590-021-01051-8. Epub 2021 Oct 5. Nat Immunol. 2021. PMID: 34611361
Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung.
Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Yuan JX. Jain PP, et al. Pulm Circ. 2020 Nov 25;10(4):2045894020956592. doi: 10.1177/2045894020956592. eCollection 2020 Oct-Dec. Pulm Circ. 2020. PMID: 33282184 Free PMC article.
Removal of extracellular Ca(2+) abolished hypoxic pulmonary vasoconstriction, while blockade of L-type voltage-dependent Ca(2+) channels (with nifedipine), non-selective cation channels (with 30 M SKF-96365), and TRPC6/TRPV1 channels (with 1 M SAR-7334 and 30 M …
Removal of extracellular Ca(2+) abolished hypoxic pulmonary vasoconstriction, while blockade of L-type voltage-dependent Ca(2+) channels (wi …